Captain John Terry could replace Luiz, who has been playing with a knee injury, while Nathan Ake and Kenedy are options to replace Alonso at left wing-back, with Cesc Fabregas among those potentially coming in.
With no midweek game next week, Chelsea are unlikely to make wholesale changes, so Diego Costa and Eden Hazard could continue.
Chelsea (from): Courtois, Begovic, Fabregas, Zouma, Kante, Hazard, Loftus-Cheek, Moses, Pedro, Costa, Matic, Willian, Batshuayi, Cahill, Terry, Azpilicueta, Chalobah, Eduardo, Aina, Ake.
